Simon J. Teague: search on Z-Library

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1

Reversibility of hyperglycaemia and islet abnormalities in the high fat-fed female ZDF rat model of type 2 diabetes

Joanne Teague, Amie Gyte, Joanne E. Peel, Kimberley C. Young, Susan J.G. Loxham, Rachel M. Mayers, Simon M. Poucher

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2011

Language:

english

File:

PDF, 1.12 MB

english, 2011

2

The Design of Leadlike Combinatorial Libraries

Simon J. Teague, Andrew M. Davis, Paul D. Leeson, Tudor Oprea

Journal:

Angewandte Chemie International Edition

Year:

1999

Language:

english

File:

PDF, 167 KB

english, 1999

3

Application and Limitations of X-ray Crystallographic Data in Structure-Based Ligand and Drug Design

Andrew M. Davis, Simon J. Teague, Gerard J. Kleywegt

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 682 KB

english, 2003

4

Use of flexible bronchoscopy in pediatric patients receiving extracorporeal membrane oxygenation (ECMO) support

Pradip P. Kamat, Jonathan Popler, Joel Davis, Traci Leong, Sarah C. Piland, Dawn Simon, Alan Harsch, William G. Teague, James D. Fortenberry

Journal:

Pediatric Pulmonology

Year:

2011

Language:

english

File:

PDF, 66 KB

english, 2011

5

Die Bedeutung der Balance von Wasserstoffbrückenbindungen und hydrophoben Wechselwirkungen im Wirkstoff-Rezeptor-Komplex

Andrew M. Davis, Simon J. Teague

Journal:

Angewandte Chemie

Year:

1999

Language:

german

File:

PDF, 1.70 MB

german, 1999

6

Design kombinatorischer Leitstruktur-Bibliotheken

Simon J. Teague, Andrew M. Davis, Paul D. Leeson, Tudor Oprea

Journal:

Angewandte Chemie

Year:

1999

Language:

german

File:

PDF, 157 KB

german, 1999

7

Hydrogen Bonding, Hydrophobic Interactions, and Failure of the Rigid Receptor Hypothesis

Andrew M. Davis, Simon J. Teague

Journal:

Angewandte Chemie International Edition

Year:

1999

Language:

english

File:

PDF, 1.69 MB

english, 1999

8

Anwendung und Grenzen kristallographischer Daten im strukturbezogenen Liganden- und Wirkstoff-Design

Andrew M. Davis, Simon J. Teague, Gerard J. Kleywegt

Journal:

Angewandte Chemie

Year:

2003

Language:

german

File:

PDF, 560 KB

german, 2003

9

ChemInform Abstract: Hydrogen Bonding, Hydrophobic Interactions, and Failure of the Rigid Receptor Hypothesis

Andrew M. Davis, Simon J. Teague

Journal:

Year:

1999

File:

PDF, 25 KB

1999

10

ChemInform Abstract: Is There a Difference Between Leads and Drugs? A Historical Perspective.

Tudor I. Oprea, Andrew M. Davis, Simon J. Teague, Paul D. Leeson

Journal:

Year:

2001

File:

PDF, 25 KB

2001

11

Application and Limitations of X-Ray Crystallographic Data in Structure-Based Ligand and Drug Design.

Andrew M. Davis, Simon J. Teague, Gerard J. Kleywegt

Journal:

Year:

2003

File:

PDF, 53 KB

2003

12

Structure-Driven HtL: Design and Synthesis of Novel Aminoindazole Inhibitors of c-Jun N-Terminal Kinase Activity.

Michael J. Stocks, Simon Barber, Rhonan Ford, Frederic Leroux, Steve St-Gallay, Simon Teague, Yafeng Xue

Journal:

Year:

2005

File:

PDF, 17 KB

2005

13

Total synthesis of Δ9(12)-capnellene-8α,10α-diol

Gerald Pattenden, Simon J. Teague

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 159 KB

english, 1982

14

Macrocyclic ring closures employing the Intramolecular Heck reaction

Michael J. Stocks, Richard P. Harrison, Simon J. Teague

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 216 KB

english, 1995

15

Facile synthesis of a o-nitrobenzyl photolabile linker for combinatorial chemistry

Journal:

Tetrahedron Letters

Year:

1996

Language:

english

File:

PDF, 183 KB

english, 1996

16

Identification of novel α7 nAChR positive allosteric modulators with the use of pharmacophore in silico screening methods

Anna Maria Capelli, Laura Castelletti, Cristian Salvagno, Beatrice Oliosi, Elisa Di Lenarda, Caterina Virginio, Andrew Lightfoot, James N.C. Kew, Simon Teague

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.11 MB

english, 2010

17

Synthesis of benzimidazole based JNK inhibitors

Simon J. Teague, Simon Barber, Sarah King, Linda Stein

Journal:

Tetrahedron Letters

Year:

2005

Language:

english

File:

PDF, 107 KB

english, 2005

18

Synthesis of 6-substituted 5-cyano-7-hydroxy-2-carboxybenzofurans

Simon J. Teague, Simon Barber

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 525 KB

english, 2010

19

Transannular cyclisation as a stratagem in synthesis. A total synthesis of (±)-pentalenene

Gerald Pattenden, Simon J. Teague

Journal:

Year:

1987

Language:

english

File:

PDF, 1.06 MB

english, 1987

20

A new synthesis of FPL 64176 and analogues: The discovery of benzoylpyrrole calcium channel activators with low nanomolar potency

Andrew J.G. Baxter, Simon J. Teague

Journal:

Year:

1993

Language:

english

File:

PDF, 328 KB

english, 1993

21

Flavanoid epoxides—VII: Flavindogenide chlorohydrins

J.R. Doherty, D.D. Keane, K.G. Marathe, W.I. O'Sullivan, E.M. Philbin, R.M. Simons, P.C. Teague

Journal:

Year:

1970

Language:

english

File:

PDF, 595 KB

english, 1970

22

Flavanoid epoxides—VI: Stereochemistry of flavindogenide epoxides

D.D. Keane, W.I. O'Sullivan, E.M. Philbin, R.M. Simons, P.C. Teague

Journal:

Year:

1970

Language:

english

File:

PDF, 832 KB

english, 1970

23

Flavanoid epoxides—XI: The stereospecific epoxidation of 3-arylideneflavanones by sodium hypochlorite

D.D. Keane, W.I. O'Sullivan, E.M. Philbin, R.M. Simons, P.C. Teague

Journal:

Year:

1971

Language:

english

File:

PDF, 346 KB

english, 1971

24

Library synthesis using solution phase capping of solid phase derived intermediates

Simon J Teague, Iain A.S Walters

Journal:

Tetrahedron Letters

Year:

2000

Language:

english

File:

PDF, 78 KB

english, 2000

25

Synthesis of Δ9(12)-capnellene-8β, 10α-diol from soft coral capnella imbricata

Mark Ladlow, Gerald Pattenden, Simon J. Teague

Journal:

Tetrahedron Letters

Year:

1986

Language:

english

File:

PDF, 117 KB

english, 1986

26

Synthesis of 3-alkylcyclopentane-1,2-diones by acid-catalysed rearrangements of α-ketoglycol derivatives

Gerarld Pattenden, Simon Teague

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 111 KB

english, 1982

27

Synthesis of (±)-pentalenene

Gerald Pattenden, Simon J. Teague

Journal:

Tetrahedron Letters

Year:

1984

Language:

english

File:

PDF, 216 KB

english, 1984

28

Synthesis and evaluation of dual domain macrocyclic FKBP12 ligands.

Moya V. Caffrey, David E. Cladingboel, Martin E. Cooper, David K. Donald, Mark Furber, David N. Hardern, Richard P. Harrison, Michael J. Stocks, Simon J. Teague

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 264 KB

english, 1994

29

The contribution to binding of the pyranoside substituents in the excised binding domain of FK-506

Michael J. Stocks, Timothy N. Birkinshaw, Simon J. Teague

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 260 KB

english, 1994

30

Electrolysis and other local ablative treatments for non-resectable colorectal liver metastases

Benjamin D. Teague, Simon A. Wemyss-Holden, Beverley G. Fosh, Ashley R. Dennison, Guy J. Maddern

Journal:

ANZ Journal of Surgery

Year:

2002

Language:

english

File:

PDF, 83 KB

english, 2002

31

Synthesis of FK506-Cyclosporin hybrid macrocycles

Simon J. Teague, Martin E. Cooper, Michael J. Stocks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 295 KB

english, 1995

32

Structure-driven HtL: Design and synthesis of novel aminoindazole inhibitors of c-Jun N-terminal kinase activity

Michael J. Stocks, Simon Barber, Rhonan Ford, Frederic Leroux, Steve St-Gallay, Simon Teague, Yafeng Xue

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 1.02 MB

english, 2005

33

Discovery of potent CRTh2 (DP2) receptor antagonists

Timothy N. Birkinshaw, Simon J. Teague, Claire Beech, Roger V. Bonnert, Stephen Hill, Anil Patel, Sara Reakes, Hitesh Sanganee, Iain G. Dougall, Tim T. Phillips, Sylvia Salter, Jerzy Schmidt, Elizabet

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 157 KB

english, 2006

34

Flavanoid epoxides V. Stereochemistry of flavindogenide epoxides

J.P. Doherty, D.D. Keane, K.G. Marathe, W.I. O'Sullivan, E.M. Philbin, R.M. Simons, P.C. Teague

Journal:

Tetrahedron Letters

Year:

1968

Language:

english

File:

PDF, 236 KB

english, 1968

35

Synthesis and study of a non macrocyclic FK506 derivative.

Simon J. Teague, Martin E. Cooper, David K. Donald, Mark Furber

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 306 KB

english, 1994

36

The affinity of the excised binding domain of FK-506 for the immunophilin FKBP12.

Simon J. Teague, Michael J. Stocks

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 258 KB

english, 1993

37

Concrete evidence of confusion

Teague, Simon J.

Journal:

Year:

2010

Language:

english

File:

PDF, 161 KB

english, 2010

38

Implications of protein flexibility for drug discovery

Teague, Simon J.

Journal:

Nature Reviews Drug Discovery

Year:

2003

Language:

english

File:

PDF, 902 KB

english, 2003

39

Solid-Phase Total Synthesis of Oscillamide Y and Analogues

Marsh, Ian R., Bradley, Mark, Teague, Simon J.

Journal:

Journal of Organic Chemistry

Year:

1997

Language:

english

File:

PDF, 180 KB

english, 1997

40

Synthesis of Heavily Substituted 2-Aminopyridines by Displacement of a 6-Methylsulfinyl Group

Teague, Simon J.

Journal:

Journal of Organic Chemistry

Year:

2008

Language:

english

File:

PDF, 89 KB

english, 2008

41

In vitro and in vivo characterization of PheTQS, a novel α7 nAChR positive allosteric modulator

James N.C. Kew, Selina Mok, Annette Weil, Caterina Virginio, Laura Castelletti, Eric Southam, Carol Jennings, Lee A. Dawson, Laurent P. Lacroix, Abbe Martyn, Simon Teague, Zeenat Atcha, Darrel Pembert

Journal:

Biochemical Pharmacology

Year:

2009

Language:

english

File:

PDF, 73 KB

english, 2009

42

Acylglycinamides as inhibitors of glycine transporter type 1

Richard Blunt, Roderick Porter, Amanda Johns, David Nash, Gemma Puckey, Paul Wyman, Hugh Herdon, Simon Teague, Victoria Hadden, Stefano Fontana, Laurie Gordon

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 908 KB

english, 2011

43

Glycine transporter 1 (GlyT1) inhibitors exhibit anticonvulsant properties in the rat maximal electroshock threshold (MEST) test

Mikhail Kalinichev, Kathryn R. Starr, Simon Teague, Andrea M. Bradford, Rod A. Porter, Hugh J. Herdon

Journal:

Year:

2010

Language:

english

File:

PDF, 633 KB

english, 2010

44

Learning lessons from drugs that have recently entered the market

Simon J. Teague

Journal:

Drug Discovery Today

Year:

2011

Language:

english

File:

PDF, 362 KB

english, 2011

45

Glucagon challenge in the rat: A robust method for the in vivo assessment of Glycogen phosphorlyase inhibitor efficacy

Susan J.G. Loxham, Joanne Teague, Simon M. Poucher, Joanne De Schoolmeester, Andrew V. Turnbull, Frank Carey

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2007

Language:

english

File:

PDF, 202 KB

english, 2007

46

Comparison of intraabdominal abscess formation after laparoscopic and open appendicectomies in children

Ramesh M. Nataraja, Warwick J. Teague, Julie Galea, Lynette Moore, Munther J. Haddad, Thomas Tsang, Sanjeev Khurana, Simon A. Clarke

Journal:

Journal of Pediatric Surgery

Year:

2012

Language:

english

File:

PDF, 143 KB

english, 2012

47

Subtotal hepatectomy: a porcine model for the study of liver regeneration

Fiona G Court, Peter E Laws, Charles P Morrison, Benjamin D Teague, Matthew S Metcalfe, Simon A Wemyss-Holden, Ashley R Dennison, Guy J Maddern

Journal:

Journal of Surgical Research

Year:

2004

Language:

english

File:

PDF, 281 KB

english, 2004

48

The lack of a systemic inflammatory response syndrome supports the safety of pancreatic electrolysis: experimental studies

Benjamin D Teague, Charles P Morrison, Fiona G Court, Trung Nguyen, Simon A Wemyss-Holden, Ashley R Dennison, Guy J Maddern

Journal:

Journal of Surgical Research

Year:

2004

Language:

english

File:

PDF, 71 KB

english, 2004

49

Synthesis of melicodenines C, D and E

Holla, Harish, Jenkins, Ian D., Neve, Juliette E., Pouwer, Rebecca H., Pham, Ngoc, Teague, Simon J., Quinn, Ronald J.

Journal:

Tetrahedron Letters

Year:

2012

Language:

english

File:

PDF, 404 KB

english, 2012

50

Configuration and conformation of 3-arylideneflavanones

Keane, D. D., Marathe, K. G., O'Sullivan, W. I., Philbin, E. M., Simons, R. M., Teague, P. C.

Journal:

Journal of Organic Chemistry

Year:

1970

Language:

english

File:

PDF, 733 KB

english, 1970

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